The next stage in molecular diagnostics: Multiplex POCT testing (xPOCT)

In recent years, POCT has been recognized as a promising in vitro diagnostic method that can provide low-cost, stable, sensitive, and specific analysis in order to replace traditional clinical laboratory diagnostic tests. The rapid development of POC diagnostics has facilitated a shift from a centralized to a decentralized, patient-centered diagnostic model.

Multiplex POCT test - xPOCT

Early diagnosis of a specific disease plays a decisive role in its effective treatment. However, in many cases, clinical evidence based on a single biomarker is insufficient to diagnose or monitor a disease, thus hindering subsequent rapid and precise treatment. 

Therefore, medical practitioners need to screen multiple targets simultaneously for rapid, cost-effective and reliable quantitative analysis. As a result, multiplex testing has become more important for immediate testing, and the demand for xPOCT devices has increased. This type of diagnostics enables laypersons to obtain the results of specialized in vitro diagnostic tests in a short period of time, while paving the way for new home health monitoring systems and providing valuable information for personalized medicine.

Multiplex POCT diagnostic technology 

Multiplex POCT diagnostic technologies (xPOCTs) can detect the presence of multiple pathogens in a sample, such as proteins, cells, DNA, RNA, exosomes and metabolites, etc. xPOCT devices based on multiple technologies can be used to detect and meet new diagnostic, predictive and therapeutic needs in the field, and can be used outside the regular laboratory, such as clinics, wards and even homes. This sophisticated system design offers effective applications and will shape the future of xPOCT systems.

The multi POCT technique can be implemented by the following methods

LATERAL FLOW ASSAYS:systems based on lateral flow analysis 

MICROFLUIDICS:microfluidics-based systems

ARRAY:array-based system

BEAD microbead-based system

Flow cell-based systems

Anitoa has undertaken product development of xPOCT instruments based on microfluidic technology.

Microfluidics can provide fully integrated xPOCT devices for sample handling, fluid processing and signal generation. Microfluidics-based devices use a unique channel design to drive delivery of small amounts of fluid, reducing assay complexity and enabling multiplex analysis and high-throughput screening.

Features of Anitoa microfluidic products.

Multiplex: one sample corresponds to multiple reaction chambers.

Multiplex: one reaction chamber corresponds to up to 8 fluorescence channels.

Fully automated: no manual operation is required after sample entry.

Simple structure: all operations are performed by the instrument and the microfluidic cartridge itself has no structural components.

More information will be introduced and released gradually.

Professional Portable qPCR System Manufacturer - Anitoa

Anitoa is a professional R&D and manufacturing company of molecular diagnostic qPCR instruments and reagents, with independent intellectual property rights of core chip technology, optical technology, rapid heating, microfluidic control and supporting reagents and other patented technologies, so that the instruments developed by Anitoa are characterized by quick and easy small instruments, allowing the development of expensive and complex large PCR instruments into truly portable POCT products.